F-Box and WD Repeat Domain Containing 8 (FBXW8) (Middle Region) Peptide
FBXW8
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits FBXW8
- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FBXW8 Antibody(ARP55586_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
- Synonymes
- FBW6 Peptide, FBW8 Peptide, FBX29 Peptide, FBXO29 Peptide, FBXW6 Peptide, 4930438M06Rik Peptide, Fbx29 Peptide, F-box and WD repeat domain containing 8 Peptide, ring finger protein, transmembrane 2 Peptide, F-box and WD-40 domain protein 8 Peptide, FBXW8 Peptide, Fbxw8 Peptide, RNFT2 Peptide
- Sujet
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FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.
Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
Protein Interaction Partner: SKP1,CUL7,RBX1,SKP1,CUL7,EP300,RBX1,SKP1
Protein Size: 598 - Poids moléculaire
- 67 kDa
- ID gène
- 26259
- NCBI Accession
- NM_153348, NP_699179
- UniProt
- Q8N3Y1
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