Forkhead Box O4 (FOXO4) (C-Term) Peptide
FOXO4
Reactivité: Humain, Souris
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits FOXO4
- FOXO4 (Forkhead Box O4 (FOXO4))
- Protein Region
- C-Term
- Origine
- Humain, Souris
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- PPVMAGAPIP KVLGTPVLAS PTEDSSHDRM PQDLDLDMYM ENLECDMDNI
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Foxo4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- FOXO4 (Forkhead Box O4 (FOXO4))
- Synonymes
- FOXO4 Peptide, foxo4 Peptide, AFX Peptide, AFX1 Peptide, MLLT7 Peptide, Afxh Peptide, Mllt7 Peptide, afx Peptide, RGD1561201 Peptide, forkhead box O4 Peptide, forkhead box O4 L homeolog Peptide, FOXO4 Peptide, foxo4.L Peptide, Foxo4 Peptide
- Sujet
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Foxo4 is a transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. It represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.
Alias Symbols: Afxh, MGC117660, Mllt7, afx
Protein Size: 505 - Poids moléculaire
- 54 kDa
- ID gène
- 54601
- NCBI Accession
- NM_001005872, NP_001005872
- UniProt
- Q99MK2
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