Glycoprotein V (Platelet) (GP5) (C-Term) Peptide
GP5
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits GP5
- GP5 (Glycoprotein V (Platelet) (GP5))
- Protein Region
- C-Term
- Origine
- Humain
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- PNSSEPWVWA QPVTTGKGQD HSPFWGFYFL LLAVQAMITV IIVFAMIKIG
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GP5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- GP5 (Glycoprotein V (Platelet) (GP5))
- Synonymes
- lib Peptide, GPV Peptide, PLGPV Peptide, CD42d Peptide, glycoprotein V platelet L homeolog Peptide, glycoprotein V platelet Peptide, glycoprotein 5 (platelet) Peptide, glycoprotein V (platelet) Peptide, gp5.L Peptide, GP5 Peptide, Gp5 Peptide
- Sujet
-
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.
Alias Symbols: CD42d
Protein Interaction Partner: F2,GP1BA,YWHAZ,GP1BA
Protein Size: 560 - Poids moléculaire
- 62 kDa
- ID gène
- 2814
- NCBI Accession
- NM_004488, NP_004479
- UniProt
- P40197
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