Hypermethylated in Cancer 1 (HIC1) (Middle Region) Peptide
HIC1
Reactivité: Humain, Souris
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits HIC1
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
- Protein Region
- Middle Region
- Origine
- Humain, Souris
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-HIC1 antibody (Catalog #: ARP38806_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
- Synonymes
- zfHIC1 Peptide, HIC1 Peptide, ZBTB29 Peptide, ZNF901 Peptide, hic-1 Peptide, AA408311 Peptide, HIC-1 Peptide, hypermethylated in cancer 1 Peptide, HIC ZBTB transcriptional repressor 1 Peptide, hic1 Peptide, HIC1 Peptide, Hic1 Peptide
- Sujet
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HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
Alias Symbols: ZBTB29, hic-1, ZNF901
Protein Interaction Partner: CTBP1,HDAC1,HIC1,SIRT1,Ctbp1,HIC1
Protein Size: 714 - Poids moléculaire
- 74 kDa
- ID gène
- 3090
- NCBI Accession
- NM_006497, NP_006488
- UniProt
- Q14526
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