Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2) Peptide
KCNQ2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits KCNQ2
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-KCNQ2 antibody (Catalog #: ARP35456_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- Synonymes
- BFNC Peptide, BFNS1 Peptide, EBN Peptide, EBN1 Peptide, EIEE7 Peptide, ENB1 Peptide, HNSPC Peptide, KCNA11 Peptide, KV7.2 Peptide, KVEBN1 Peptide, KQT2 Peptide, Nmf134 Peptide, mKQT2.3 Peptide, mKQT2.4 Peptide, zgc:171872 Peptide, potassium voltage-gated channel subfamily Q member 2 Peptide, potassium voltage-gated channel, subfamily Q, member 2 Peptide, potassium voltage-gated channel subfamily KQT member 2 Peptide, potassium voltage-gated channel, KQT-like subfamily, member 2a Peptide, KCNQ2 Peptide, Kcnq2 Peptide, LOC100537363 Peptide, kcnq2a Peptide
- Sujet
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The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
Alias Symbols: BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1, BFNS1, EIEE7
Protein Interaction Partner: ARIH2,CALM1,CALM3,CALM3,KCNQ3,PRKCA,ARIH2,CALM2,CALM3,KCNQ1,KCNQ3
Protein Size: 844 - Poids moléculaire
- 93 kDa
- ID gène
- 3785
- NCBI Accession
- NM_004518, NP_004509
- UniProt
- Q5VYT9
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