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KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Peptide

KHDRBS1 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN978879
  • Antigène Tous les produits KHDRBS1
    KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
    Origine
    Humain
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-KHDRBS1 antibody (Catalog #: ARP40665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
    Synonymes
    Sam68 Peptide, p62 Peptide, p68 Peptide, fj90g10 Peptide, khdrbs1 Peptide, wu:fa18g12 Peptide, wu:fa56c01 Peptide, wu:fc91b01 Peptide, wu:fj90g10 Peptide, zgc:113899 Peptide, KHDRBS1 Peptide, P62 Peptide, khdrbs1l Peptide, sb:cb97 Peptide, wu:fb07d11 Peptide, wu:fi43c05 Peptide, zgc:85948 Peptide, KH RNA binding domain containing, signal transduction associated 1 Peptide, KH domain containing, RNA binding, signal transduction associated 1a Peptide, KH domain containing, RNA binding, signal transduction associated 1 Peptide, KH domain containing, RNA binding, signal transduction associated 1 S homeolog Peptide, KH domain containing, RNA binding, signal transduction associated 1b Peptide, KHDRBS1 Peptide, khdrbs1a Peptide, khdrbs1 Peptide, Khdrbs1 Peptide, khdrbs1.S Peptide, khdrbs1b Peptide
    Sujet
    KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

    Alias Symbols: FLJ34027, Sam68, p62, p68

    Protein Interaction Partner: GRAP2,GRB2,HCK,HNRNPK,HNRNPK,LCK,PIK3R1,RASA1,SRC,src,BTK,CBL,CDK1,CREBBP,DHX9,EMG1,FNBP4,FYN,GRAP,GRAP2,GRB2,HCK,HNRNPK,INSR,ITK,JAK3,KHDRBS1,KHDRBS3,LCK,LYN,MAPK1,NCF1,NCK1,PIK3R1,PLCG1,PLCG2,PRMT1,PTK6,PTPN6,RAPSN,RASA1,SMAD2,SMARCA2,SRC,STAT3,STUB1,TUBB3,UBA52,WBP4,YTHDC1,BTK,CREBBP,CRK,DHX9,EMG1,FNBP4,FYN,GRAP2,GRB2,Grap2,HNRNPK,INSR,IRS1,ITK,KHDRBS1,KHDRBS2,Khdrbs3,LCK,NCF1,NCK1,PACSIN1,PACSIN2,PACSIN3,PIK3R1,PLCG1,PRMT1,PTK6,RAPSN,RASA1,SRC,STAT3,STUB1,TNFSF11,TUBB3,WBP4,YTHDC1

    Protein Size: 443
    Poids moléculaire
    48 kDa
    ID gène
    10657
    NCBI Accession
    NM_006559, NP_006550
    UniProt
    Q07666
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