This is a synthetic peptide designed for use in combination with anti-KHDRBS2 Antibody(ARP53109_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: EWSR1,GRB2,HNRNPK,KHDRBS3,PRMT1,RBMX,YTHDC1,ARID2,DDX17,DDX5,DEK,DSG1,EHBP1,EWSR1,FBXW11,FGA,FGB,FGG,HNRNPA0,HNRNPA1,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPR,HNRNPUL2,HNRPDL,HRNR,HSP90AB1,IGF2BP1,IGF2BP3,ILF2,ILF3,KHDRBS1,KHDRBS3,LRRC1