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Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) (Middle Region) Peptide

MAP4K5 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN979787
  • Antigène Tous les produits MAP4K5
    MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-MAP4K5 antibody (Catalog #: ARP33101_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
    Synonymes
    GCKR Peptide, KHS Peptide, KHS1 Peptide, MAPKKKK5 Peptide, 4432415E19Rik Peptide, RGD1562028 Peptide, fl74c10 Peptide, wu:fl74c10 Peptide, zgc:55719 Peptide, zgc:55985 Peptide, mitogen-activated protein kinase kinase kinase kinase 5 Peptide, mitogen-activated protein kinase kinase kinase kinase 5 S homeolog Peptide, MAP4K5 Peptide, Map4k5 Peptide, map4k5 Peptide, map4k5.S Peptide
    Sujet
    MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

    Alias Symbols: GCKR, KHS, KHS1, MAPKKKK5

    Protein Interaction Partner: ABL1,BCR,CRK,CRKL,GRB2,TANK,TRAF2,CRK,CRKL,TRAF2

    Protein Size: 846
    Poids moléculaire
    95 kDa
    ID gène
    11183
    NCBI Accession
    NM_006575, NP_006566
    UniProt
    Q9Y4K4
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