Myocyte Enhancer Factor 2A (MEF2A) (N-Term) Peptide
MEF2A
Reactivité: Humain, Drosophila melanogaster
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits MEF2A
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Protein Region
- N-Term
- Origine
- Humain, Drosophila melanogaster
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MEF2A antibody (Catalog #: ARP38633_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Synonymes
- ADCAD1 Peptide, RSRFC4 Peptide, RSRFC9 Peptide, mef2 Peptide, A430079H05Rik Peptide, mef2a Peptide, wu:fd19d02 Peptide, adcad1 Peptide, rsrfc4 Peptide, rsrfc9 Peptide, sl2 Peptide, MEF2A Peptide, xmef2a Peptide, myocyte enhancer factor 2A Peptide, myocyte enhancer factor 2aa Peptide, myocyte enhancer factor 2a Peptide, myocyte-specific enhancer factor 2A Peptide, myocyte-specific enhancer factor 2a, putative Peptide, myocyte enhancer factor 2A L homeolog Peptide, MEF2A Peptide, Mef2a Peptide, mef2aa Peptide, EDI_092490 Peptide, EDI_038250 Peptide, Smp_161530 Peptide, mef2a.L Peptide, mef2a Peptide, LOC539054 Peptide
- Sujet
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The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
Protein Interaction Partner: ASCL1,CASP3,CASP7,CDK5,EP300,HDAC4,HDAC5,HDAC9,MAPK14,MAPK7,MEF2A,MEF2D,MYOD1,MYOG,PHB2,SMAD2,SMAD4,SUMO1,TEAD1,THRA,ASCL1,EP300,HDAC4,HDAC5,HDAC9,MAPK14,MAPK7,MEF2D,MYOG,SMAD2,THRA,VGLL4
Protein Size: 507 - Poids moléculaire
- 55 kDa
- ID gène
- 4205
- NCBI Accession
- NM_005587, NP_005578
- UniProt
- Q02078
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