This is a synthetic peptide designed for use in combination with anti-MTMR6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
MTMR6
(Myotubularin Related Protein 6 (MTMR6))
Synonymes
4022440C11Rik Peptide, AI428804 Peptide, AU041072 Peptide, zgc:55289 Peptide, wu:fi04a11 Peptide, si:dkey-286f3.1 Peptide, zgc:56405 Peptide, myotubularin related protein 6 Peptide, myotubularin related protein 8 Peptide, MTMR6 Peptide, Mtmr6 Peptide, mtmr6 Peptide, mtmr8 Peptide
Sujet
MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.