N-Acetylneuraminic Acid Synthase (NANS) (C-Term) Peptide
NANS
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits NANS
- NANS (N-Acetylneuraminic Acid Synthase (NANS))
- Protein Region
- C-Term
- Origine
- Humain
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NANS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Antigène
- NANS (N-Acetylneuraminic Acid Synthase (NANS))
- Synonymes
- MGC84329 Peptide, SAS Peptide, N-acetylneuraminate synthase L homeolog Peptide, N-acetylneuraminate synthase Peptide, nans.L Peptide, NANS Peptide, Nans Peptide
- Sujet
-
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Alias Symbols: SAS
Protein Interaction Partner: DDA1,UBC
Protein Size: 359 - Poids moléculaire
- 40 kDa
- ID gène
- 54187
- NCBI Accession
- NM_018946, NP_061819
- UniProt
- Q9NR45
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