Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) Peptide
NDFIP2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits NDFIP2
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NDFIP2 Antibody(ARP49441_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
- Synonymes
- MGC68708 Peptide, DKFZp459H0627 Peptide, N4WBP5A Peptide, 0710001O20Rik Peptide, 2810436B12Rik Peptide, 9130207N19Rik Peptide, N4wbp5a Peptide, mKIAA1165 Peptide, Nedd4 family interacting protein 2 S homeolog Peptide, Nedd4 family interacting protein 2 Peptide, ndfip2.S Peptide, NDFIP2 Peptide, ndfip2 Peptide, Ndfip2 Peptide
- Sujet
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NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: ITCH,NEDD4,NEDD4L,SMURF1,WWP2,NEDD4,SLC11A2
Protein Size: 336 - Poids moléculaire
- 36 kDa
- ID gène
- 54602
- NCBI Accession
- NM_019080, NP_061953
- UniProt
- Q9NV92
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