Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Peptide
NFKB2
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits NFKB2
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NFKB2 antibody (Catalog #: ARP32718_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Synonymes
- NF-kappaB2 Peptide, lyt Peptide, p49 Peptide, p49/p100 Peptide, p50B Peptide, p52 Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 Peptide, Nfkb2 Peptide
- Sujet
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NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Alias Symbols: p52, p105, H2TF1, LYT10, LYT-10, NF-kB2
Protein Interaction Partner: BCL3,NFKBIE,BCL3,BTRC,CHUK,DDX3X,GLG1,GTF2I,HDAC4,HDAC5,IKBKB,IKBKG,MAP3K14,MAP3K8,MEN1,NFKB1,NFKBIA,NFKBIB,NFKBIE,NKRF,NR3C1,NR5A1,PSMD11,REL,RELA,RELB,RPL30,RPL6,RPS13,TNIP2,TSC22D3,USP2,BCL3,BTRC,DDX3X,FBXW7,GLG1,IKBKG,MAP3K14,MAP3K8,MEN1,NFKB1,NFKB2,NFKBIE,NKRF,NR3C1,REL,RELA,RELB,RPL30,RPL6,RPS13,SEC16A,SP1,SUMO1,TBK1,TNIP2,TSC22D3,UBC,USP2
Protein Size: 933 - Poids moléculaire
- 101 kDa
- ID gène
- 4791
- NCBI Accession
- NM_002502, NP_002493
- UniProt
- Q00653
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