This is a synthetic peptide designed for use in combination with anti-NFYB Antibody(ARP31262_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: CBF-A, CBF-B, HAP3, NF-YB
Protein Interaction Partner: MYC,C1QBP,CEBPZ,CIITA,CNTN2,CSDA,DRAP1,ELF1,EP300,MYC,NFYA,NFYC,SP1,TBP,TP53,TP73,YBX1,CEBPZ,CNTN2,DRAP1,EP300,GRB2,KAT2B,MYC,NFYA,NFYC,TAF11,TAF12,TAF6,TBP,TP53,TP73