NME1
(Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
Protein Region
N-Term
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Dot Blot (DB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-NME1 antibody (Catalog #: AVARP00009_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Protein Interaction Partner: HHV4gp086,APEX1,AURKA,GORASP2,ITGB1,KSR1,MIF,NME1,NME3,NME4,POLR1C,PRUNE,RORA,RORB,RRAD,SET,TERF1,TIAM1,WDYHV1,AURKA,GORASP2,ITGB1,NME1,NME3,NME4,POLR1C,PRUNE,RAC1,RORA,RORB,RRAD,SET,TERF1,TIAM1,USP18,WDYHV1