Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) Peptide
NR1D2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits NR1D2
- NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NR1D2 antibody (Catalog #: ARP38567_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
- Synonymes
- BD73 Peptide, EAR-1R Peptide, RVR Peptide, HZF-2 Peptide, Rev-erb Peptide, REV-ERBB Peptide, NR1D2 Peptide, rvr Peptide, bd73 Peptide, hzf2 Peptide, ear-1r Peptide, hs.37288 Peptide, NR1D2-A Peptide, Reverbbeta-A Peptide, reverbb1 Peptide, reverbb Peptide, reverbb2 Peptide, zgc:92019 Peptide, nuclear receptor subfamily 1 group D member 2 Peptide, nuclear receptor subfamily 1, group D, member 2 Peptide, nuclear receptor subfamily 1, group D, member 2a Peptide, nuclear receptor subfamily 1, group D, member 2b Peptide, NR1D2 Peptide, Nr1d2 Peptide, nr1d2 Peptide, nr1d2a Peptide, nr1d2b Peptide
- Sujet
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NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Alias Symbols: BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
Protein Interaction Partner: CUL1,NCOA5,NCOR1,NR1D1,RGN,UBE2I,NCOR1
Protein Size: 579 - Poids moléculaire
- 65 kDa
- ID gène
- 9975
- NCBI Accession
- NM_005126, NP_005117
- UniProt
- Q14995
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