Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (N-Term) Peptide
NR2C2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits TR4 (NR2C2)
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NR2C2 antibody (Catalog #: ARP38288_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- Synonymes
- TAK1 Peptide, TR2R1 Peptide, TR4 Peptide, hTAK1 Peptide, Tr4 Peptide, gb:dq017625 Peptide, im:6911408 Peptide, mKIAA4145 Peptide, nuclear receptor subfamily 2 group C member 2 Peptide, nuclear receptor subfamily 2, group C, member 2 Peptide, NR2C2 Peptide, Nr2c2 Peptide, nr2c2 Peptide
- Sujet
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Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TAK1, TR2R1, TR4, hTAK1
Protein Interaction Partner: AR,CDC37,CHUK,ESR1,FKBP5,HNF4A,HSP90AA1,HSP90AB1,IKBKB,JAZF1,NR2C1,NR2C2AP,PEBP1,RXRB,TAB1,TAB2,TRAF2,AR,ESR1,HDAC3,HDAC4,HNF4A,NR2C2AP
Protein Size: 615 - Poids moléculaire
- 67 kDa
- ID gène
- 7182
- NCBI Accession
- NM_003298, NP_003289
- UniProt
- P49116
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