NR5A1
(Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
Protein Region
Middle Region
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-NR5A1 antibody (Catalog #: ARP45619_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
NR5A1
(Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
Synonymes
AD4BP Peptide, ELP Peptide, FTZ1 Peptide, FTZF1 Peptide, POF7 Peptide, SF-1 Peptide, SF1 Peptide, SPGF8 Peptide, SRXY3 Peptide, Ad4BP Peptide, ELP-3 Peptide, Ftz-F1 Peptide, Ftzf1 Peptide, Ad4BP/SF-1 Peptide, Ad4bp Peptide, Sf-1 Peptide, NR5A1 Peptide, sf-1 Peptide, elp Peptide, sf1 Peptide, ftz1 Peptide, ad4bp Peptide, ftzf1 Peptide, SF-1/Ad4BP Peptide, SI:zC167P9.2 Peptide, ff1d Peptide, nr5a2l Peptide, nuclear receptor subfamily 5 group A member 1 Peptide, nuclear receptor subfamily 5, group A, member 1 Peptide, nuclear receptor subfamily 5 group A member 1 L homeolog Peptide, nuclear receptor subfamily 6 group A member 1 Peptide, nuclear receptor subfamily 5, group A, member 1b Peptide, NR5A1 Peptide, Nr5a1 Peptide, nr5a1.L Peptide, nr5a1 Peptide, NR6A1 Peptide, nr5a1b Peptide
Sujet
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interaction Partner: AR,CTNNB1,EDF1,GATA4,GTF2B,JUN,MAPK1,NCOA1,NFKB2,NFYA,NR0B1,NRIP1,PIAS1,PITX1,PNRC2,PROX1,SMARCD3,SOX2,SOX8,SOX9,SP1,TBX19,TRERF1,ZNF653,CTNNB1,EDF1,GATA4,GTF2B,JUN,NCOA1,NR0B1,NRIP1,PITX1,SOX9,SP1,TRERF1,ZNF653