Blocking Peptide (BP), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-PSMC5 antibody (Catalog #: ARP38192_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification
Purified
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Alias Symbols: S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Protein Interaction Partner: ERCC3,ESR1,FOS,GTF2B,KRT15,MYO18B,NR1I2,PSMC3,PSMC4,RORA,RXRA,SP1,TAF10,THRB,TNNT1,VDR,ADRM1,ATXN7,ERCC3,KRT15,PAAF1,PSMC1,PSMC3,PSMC4,PSMC6,PSMD1,PSMD10,PSMD13,PSMD6,PSMD7,PTGS2,RORA,SP1,THRB,TNNT1,UBE3C,UCHL5,USP14