Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1) (Middle Region) Peptide
PSMF1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits PSMF1
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- DYIDAEHLGD FHRTYKNSEE LRSRIVSGII TPIHEQWEKA NVSSPHREFP
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PSMF1 Antibody(ARP59167_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Synonymes
- PI31 Peptide, AW048666 Peptide, BC012260 Peptide, zgc:92785 Peptide, proteasome inhibitor subunit 1 Peptide, proteasome (prosome, macropain) inhibitor subunit 1 Peptide, PSMF1 Peptide, Psmf1 Peptide, psmf1 Peptide
- Sujet
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Alias Symbols: PI31
Protein Interaction Partner: BEND7,CCDC85B,CD2BP2,CTBP2,HOOK2,KHDRBS3,MAGEA11,NUDT21,PDLIM7,QKI,RBFOX1,RBMX,RHOXF2,RNF126,SMCR7,TRAF2,BEND7,CCDC85B,CTBP2,FBXO7,HOOK2,KHDRBS3,MAGEA11,NUDT21,PDLIM7,RBMX,RHOXF2,RNF126,SMCR7,TRAF2
Protein Size: 271 - Poids moléculaire
- 30 kDa
- ID gène
- 9491
- NCBI Accession
- NM_006814, NP_006805
- UniProt
- Q92530
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