This is a synthetic peptide designed for use in combination with anti-PTPRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PTPRN
Reactivité: Humain, Souris
Hôte: Synthetic
BP, BI
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
PTPRN
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
Synonymes
IA-2 Peptide, IA-2/PTP Peptide, IA2 Peptide, ICA512 Peptide, R-PTP-N Peptide, mIA-A Peptide, mKIAA4064 Peptide, Ia-2 Peptide, fc43c04 Peptide, ptprn Peptide, wu:fc43c04 Peptide, ia-2 Peptide, ia2 Peptide, ica512 Peptide, r-ptp-n Peptide, protein tyrosine phosphatase, receptor type N Peptide, protein tyrosine phosphatase, receptor type, N Peptide, protein tyrosine phosphatase, receptor type, Na Peptide, protein tyrosine phosphatase, receptor type N L homeolog Peptide, PTPRN Peptide, Ptprn Peptide, ptprna Peptide, ptprn.L Peptide
Sujet
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Alias Symbols: IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP