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RB1-Inducible Coiled-Coil 1 (RB1CC1) Peptide

RB1CC1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN982703
  • Antigène Tous les produits FIP200 (RB1CC1)
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Origine
    Humain
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-RB1CC1 antibody (Catalog #: ARP50467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Synonymes
    DKFZp459E2330 Peptide, CC1 Peptide, FIP200 Peptide, 2900055E04Rik Peptide, 5930404L04Rik Peptide, Cc1 Peptide, LaXp180 Peptide, RB1 inducible coiled-coil 1 Peptide, RB1 inducible coiled-coil 1 L homeolog Peptide, RB1-inducible coiled-coil 1 Peptide, RB1CC1 Peptide, rb1cc1.L Peptide, rb1cc1 Peptide, Rb1cc1 Peptide
    Sujet
    RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.

    Alias Symbols: CC1, DRAGOU14, FIP200

    Protein Interaction Partner: PTK2,PTK2B,CDK19,DBNL,ERCC6L,MAP3K5,MOBKL3,PTK2,PTK2B,TRAF2

    Protein Size: 1591
    Poids moléculaire
    183 kDa
    ID gène
    9821
    NCBI Accession
    NM_001083617, NP_001077086
    UniProt
    Q8TDY2
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