SIN3B
(SIN3 Transcription Regulator Homolog B (SIN3B))
Protein Region
Middle Region
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-SIN3B antibody (Catalog #: ARP50590_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SIN3B
Reactivité: Humain, Souris, Singe
Hôte: Synthetic
BP
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
SIN3B
(SIN3 Transcription Regulator Homolog B (SIN3B))
Synonymes
fj63d08 Peptide, si:dkey-6n6.6 Peptide, wu:fj63d08 Peptide, 2810430C10Rik Peptide, SIN3 transcription regulator family member B Peptide, SIN3 transcription regulator family member B S homeolog Peptide, transcriptional regulator, SIN3B (yeast) Peptide, sin3b Peptide, SIN3B Peptide, sin3b.S Peptide, Sin3b Peptide
Sujet
SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription
Alias Symbols: KIAA0700
Protein Interaction Partner: HDAC1,HDAC9,IKZF1,IKZF4,MAD1L1,MXD1,MXI1,REST,SETDB1,ZBTB16,HCFC1,HDAC1,HDAC9,IKZF1,IKZF2,IKZF3,IKZF4,MECP2,RNF220,SAP30,SETDB1,SUDS3,WHSC1,ZBTB16