SLC25A14
(Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-SLC25A14 antibody (Catalog #: ARP43861_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
SLC25A14
(Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14 (SLC25A14))
Synonymes
ATPUMP5 Peptide, DIC1 Peptide, DICARBOXYLATE CARRIER 1 Peptide, F14M13.10 Peptide, F14M13_10 Peptide, PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5 Peptide, uncoupling protein 5 Peptide, zgc:55596 Peptide, BMCP1 Peptide, UCP5 Peptide, BMCP-1 Peptide, Ucp5 Peptide, UCP5L Peptide, UCP5S Peptide, Bmcp1 Peptide, solute carrier family 25 member 14 Peptide, uncoupling protein 5 Peptide, solute carrier family 25 (mitochondrial carrier, brain), member 14 Peptide, SLC25A14 Peptide, UCP5 Peptide, slc25a14 Peptide, Slc25a14 Peptide
Sujet
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. SLC25A14 has an N-terminal hydrophobic domain that is not present in other UCPs.