SMAD6
(SMAD, Mothers Against DPP Homolog 6 (SMAD6))
Origine
Humain, Drosophila melanogaster
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-SMAD6 antibody (Catalog #: ARP32690_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Alias Symbols: MADH6, MADH7, HsT17432
Protein Interaction Partner: BMPR1B,HOXC8,MAP3K7,RNF111,RUNX2,SMAD1,SMAD7,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TOB1,CTBP1,HOXC8,MAP3K7,PIAS4,RNF111,SMAD1,SMAD2,SMAD4,SMAD7,STAMBP,STRAP,TAB1,YAP1