SMAD, Mothers Against DPP Homolog 7 (SMAD7) Peptide
SMAD7
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits SMAD7
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SMAD7 antibody (Catalog #: ARP32008_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Synonymes
- CRCS3 Peptide, MADH7 Peptide, MADH8 Peptide, Smad7a Peptide, Madh7 Peptide, Smad10 Peptide, madh7 Peptide, xsmad7 Peptide, wu:fj60c10 Peptide, SMAD family member 7 Peptide, SMAD family member 7 L homeolog Peptide, SMAD7 Peptide, Smad7 Peptide, smad7.L Peptide, smad7 Peptide
- Sujet
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Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Alias Symbols: CRCS3, MADH7, MADH8
Protein Interaction Partner: SMURF1,SMURF2,ACVR1B,AKT1,ASH1L,AXIN1,BMPR1B,CTNNB1,CXXC5,DVL1,EP300,ERBB2IP,HAT1,HEYL,KDM2A,MAP2K3,MAP2K6,MAP3K7,MAPK14,MBD1,MYOD1,PARD3,PIAS1,PIAS4,RNF111,SASH3,SMAD6,SMAD7,SMURF1,SMURF2,SOX13,SOX5,SOX7,STAMBP,STAMBPL1,STRAP,TAB1,TGFBR1,TGFBR2,TTF1,TTF2,XRCC6,YAP1,ZBTB11,ZBTB44,ZNF107,ACVR1B,AKT1,BMPR1A,CTNNB1,DVL1,EP300,ERBB2IP,LEF1,MAP2K3,MAP2K6,MAP3K7,MAPK14,PARD3B,PIAS4,RNF111,SMAD2,SMAD3,SMAD4,SMAD6,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TGFBR2,Wwp2,YAP1
Protein Size: 426 - Poids moléculaire
- 46 kDa
- ID gène
- 4092
- NCBI Accession
- NM_005904, NP_005895
- UniProt
- O15105
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