This is a synthetic peptide designed for use in combination with anti-TIMP3 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Alias Symbols: HSMRK222, K222, K222TA2, SFD
Protein Interaction Partner: ADAM17,EFEMP1,KDR,MMP13,MMP14,MMP2,MMP3,MMP9,ADAM17,MMP2