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Tumor Protein P63 (TP63) (N-Term) Peptide

TP63 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN985396
  • Antigène Tous les produits p63 (TP63)
    p63 (TP63) (Tumor Protein P63 (TP63))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-TP63 antibody (Catalog #: ARP33998_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    p63 (TP63) (Tumor Protein P63 (TP63))
    Synonymes
    AIS Peptide, B(p51A) Peptide, B(p51B) Peptide, EEC3 Peptide, KET Peptide, LMS Peptide, NBP Peptide, OFC8 Peptide, RHS Peptide, SHFM4 Peptide, TP53CP Peptide, TP53L Peptide, TP73L Peptide, p40 Peptide, p51 Peptide, p53CP Peptide, p63 Peptide, p73H Peptide, p73L Peptide, TP63 Peptide, tp63 Peptide, DNp63 Peptide, id:ibd3516 Peptide, tp73l Peptide, wu:fc89f04 Peptide, wu:fk85h07 Peptide, wu:fk88b02 Peptide, Ket Peptide, P73l Peptide, Tp73l Peptide, Trp63 Peptide, TRP63 Peptide, AI462811 Peptide, P51/P63 Peptide, P63 Peptide, Tp63 Peptide, Trp53rp1 Peptide, Xp63 Peptide, ket Peptide, np63 Peptide, tp73l-A Peptide, trp63 Peptide, tumor protein p63 Peptide, transformation related protein 63 Peptide, tumor protein p63 L homeolog Peptide, TP63 Peptide, tp63 Peptide, Tp63 Peptide, Trp63 Peptide, tp63.L Peptide
    Sujet
    This protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

    Alias Symbols: B(p51A), B(p51B), EEC3, KET, LMS, OFC8, RHS, SHFM4, TP73L, p51, p63, p73H, p73L, AIS, NBP, p40, TP53L, p53CP, TP53CP

    Protein Interaction Partner: FAS,DAXX,EP300,GRB2,HIPK2,HNRNPAB,PPP1R13B,PPP2R5A,TP53,TP63,TP73,WT1,BTRC,GNB2L1,HIPK2,HNRNPAB,SFRS15,UBC,YAP1

    Protein Size: 680
    Poids moléculaire
    77 kDa
    ID gène
    8626
    NCBI Accession
    NM_003722, NP_003713
    UniProt
    Q9H3D4
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