This is a synthetic peptide designed for use in combination with anti-TSEN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L
Protein Interaction Partner: RANBP10,CLP1,TSEN15,TSEN34,TSEN54