X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (C-Term) Peptide
XRCC3
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits XRCC3
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LADRLREEEA ALGCPARTLR VLSAPHLPPS SCSYTISAEG VRGTPGTQSH
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-XRCC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Synonymes
- CMM6 Peptide, 4432412E01Rik Peptide, AI182522 Peptide, AW537713 Peptide, MGC69118 Peptide, im:7142103 Peptide, zgc:101608 Peptide, si:dkey-11b8.1 Peptide, xrcc3 Peptide, XRCC3 Peptide, X-ray repair cross complementing 3 Peptide, X-ray repair complementing defective repair in Chinese hamster cells 3 Peptide, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog Peptide, XRCC3 Peptide, Xrcc3 Peptide, xrcc3.L Peptide, xrcc3 Peptide
- Sujet
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: CMM6
Protein Interaction Partner: FANCG,RAD51C,RAD51L3,BRCA2,FANCG,RAD51,RAD51C,ZNHIT3
Protein Size: 346 - Poids moléculaire
- 38 kDa
- ID gène
- 7517
- NCBI Accession
- NM_005432, NP_005423
- UniProt
- O43542
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