YY1 Associated Factor 2 (YAF2) (Middle Region) Peptide
YAF2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits YAF2
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-YAF2 antibody (Catalog #: ARP32676_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Synonymes
- MGC75686 Peptide, YAF2 Peptide, zgc:136577 Peptide, si:ch211-155a11.5 Peptide, 2810021M11Rik Peptide, YY1 associated factor 2 Peptide, YY1-associated factor 2 Peptide, yaf2 Peptide, YAF2 Peptide, LOC100221270 Peptide, Yaf2 Peptide
- Sujet
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YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
Alias Symbols: MGC41856
Protein Interaction Partner: GABPB1,MYCN,YY1,CBX3,YY1
Protein Size: 180 - Poids moléculaire
- 20 kDa
- ID gène
- 10138
- NCBI Accession
- NM_005748, NP_005739
- UniProt
- Q8IY57
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