POLB Produits
(Polymerase (DNA Directed), beta (POLB))
Catégories
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].
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Catégories POLB en vedette
POLB Anticorps
High quality antibodies with extensive validation data.
POLB Kits ELISA
Reliable ELISA kits for a wide range of species.
POLB Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
POLB recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
N° du produit
ABIN3022385
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
N° du produit
ABIN1327635
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6264332
Quantité
100 μL
Fiche technique
Fiche technique
POLB recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958686
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381085
Quantité
96 tests
Fiche technique
Fiche technique
POLB recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124515
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124514
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315620
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits POLB
: "DNA polymerase beta participates in mitochondrial DNA repair." dans: Molecular and cellular biology, (2017) (PubMed).: "p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0146031, (2016) (PubMed).
: "Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade." dans: Biochemical pharmacology, Vol. 105, pp. 23-33, (2016) (PubMed).
: "ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli." dans: DNA repair, Vol. 45, pp. 44-55, (2016) (PubMed).
: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." dans: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).
: "Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 28, pp. 8602-7, (2015) (PubMed).
: "miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium." dans: Toxicology letters, Vol. 229, Issue 1, pp. 319-26, (2014) (PubMed).
: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." dans: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).
: "The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death." dans: Nature cell biology, Vol. 12, Issue 6, pp. 563-71, (2010) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." dans: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à POLB
polymerase (DNA directed), beta (polb), DNA polymerase beta (POLB), DNA polymerase X family protein (polB), polymerase (DNA directed), beta S homeolog (polb.S), polymerase (DNA directed), beta (Polb), DNA polymerase beta (Polb), A430088C08Rik, DDBDRAFT_0186152, DDBDRAFT_0215784, DDBDRAFT_0232376, DDB_0186152, DDB_0215784, DDB_0232376, POLB, wu:fa97a05, zgc:109924Protein level used designations for POLB
- DNA-directed DNA polymerase beta
- DNA polymerase beta
- polymerase (DNA directed), beta
- DNA polymerase beta-like
- DNA pol beta
- DNA polymerase beta subunit
- mutant DNA polymerase beta
- Pol beta
- polymerase-beta
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