Profil protéine

This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Alternative names and synonyms associated with EEF1E1

• eukaryotic translation elongation factor 1 epsilon 1 (EEF1E1) anticorps
• eukaryotic translation elongation factor 1 epsilon 1 L homeolog (eef1e1.L) anticorps
• eukaryotic translation elongation factor 1 epsilon 1 (eef1e1) anticorps
• eukaryotic translation elongation factor 1 epsilon 1 (Eef1e1) anticorps

• 1110003A02Rik anticorps
• AIMP3 anticorps
• P18 anticorps

Protein level used designations for EEF1E1

eukaryotic translation elongation factor 1 epsilon 1 , eukaryotic translation elongation factor 1 epsilon-1 , ARS-interacting multifunctional protein 3 , aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 , multisynthase complex auxiliary component p18 , p18 component of aminoacyl-tRNA synthetase complex , elongation factor p18 , multisynthetase complex auxiliary component p18 , Elongation factor p18 , Multisynthase complex auxiliary component p18