IGF2 Protein (AA 30-180, partial) (GST tag)

N° du produit ABIN1047204

Détail du produit

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Type de proteíne: Recombinant

Attributs du protein: AA 30-180, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IGF2 protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS), ELISA

Séquence: ETLCGGELVD TLQFVCGDRG FYFSRPASRV SRRSRGIVEE CCFRSCDLAL LETYCATPAK SERDVSTPPT VLPDNFPRYP VGKFFQYDTW KQSTQRLRRG LPALLRARRG HVLAKELEAF REAKRHRPLI ALPTQDPAHG GAPPEMASNR K

Attributs du produit: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Ref.27 Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

Pureté: 90 %

Information d'application

Commentaires:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS buffer, 20mM GSH

Stock: -20 °C

Référence

Shen, Daimon, Wang, Jansen, Ilan: "Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 6, pp. 1947-51, (1988) (PubMed).

Irminger, Rosen, Humbel, Villa-Komaroff: "Tissue-specific expression of insulin-like growth factor II mRNAs with distinct 5' untranslated regions." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6330-4, (1987) (PubMed).

de Pagter-Holthuizen, van Schaik, Verduijn, van Ommen, Bouma, Jansen, Sussenbach: "Organization of the human genes for insulin-like growth factors I and II." dans: FEBS letters, Vol. 195, Issue 1-2, pp. 179-84, (1986) (PubMed).

Dull, Gray, Hayflick, Ullrich: "Insulin-like growth factor II precursor gene organization in relation to insulin gene family." dans: Nature, Vol. 310, Issue 5980, pp. 777-81, (1984) (PubMed).

Bell, Merryweather, Sanchez-Pescador, Stempien, Priestley, Scott, Rall: "Sequence of a cDNA clone encoding human preproinsulin-like growth factor II." dans: Nature, Vol. 310, Issue 5980, pp. 775-7, (1984) (PubMed).

Détail du antigène

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Autre désignation: Insulin-Like Growth Factor II (IGF2 Produits)

Synonymes: C11orf43 Protein, IGF-II Protein, PP9974 Protein, LOC100136550 Protein, igf2 Protein, igf2b Protein, wu:fc26e03 Protein, zgc:91781 Protein, igf-2 Protein, insigf Protein, pp9974 Protein, AL033362 Protein, Igf-2 Protein, Igf-II Protein, M6pr Protein, Mpr Protein, Peg2 Protein, IGFII Protein, RNIGF2 Protein, IGF-II-B Protein, igf2-a Protein, igf2-b Protein, insulin like growth factor 2 Protein, insulin-like growth factor II Protein, insulin-like growth factor 2a Protein, insulin like growth factor 2 S homeolog Protein, insulin-like growth factor 2 Protein, insulin-like growth factor 2 (somatomedin A) Protein, insulin like growth factor 2 L homeolog Protein, IGF2 Protein, LOC100136550 Protein, igf2a Protein, igf2.S Protein, Igf2 Protein, igf2.L Protein

Sujet: Synonyms: IGF-II,Somatomedin-A

Poids moléculaire: 44.5 kD

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation