APOA1 Protein (AA 19-267) (His tag)

N° du produit ABIN1096035

Détail du produit

Antigène: APOA1 (Apolipoprotein A-I (APOA1))

Type de proteíne: Recombinant

Attributs du protein: AA 19-267

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette APOA1 protéine est marqué à la His tag.

Fonction: Recombinant Human Apolipoprotein A1/ApoA1 (C-6His)

Séquence: RHFWQQDEPP QSPWDRVKDL ATVYVDVLKD SGRDYVSQFE GSALGKQLNL KLLDNWDSVT STFSKLREQL GPVTQEFWDN LEKETEGLRQ EMSKDLEEVK AKVQPYLDDF QKKWQEEMEL YRQKVEPLRA ELQEGARQKL HELQEKLSPL GEEMRDRARA HVDALRTHLA PYSDELRQRL AARLEALKEN GGARLAEYHA KATEHLSTLS EKAKPALEDL RQGLLPVLES FKVSFLSALE EYTKKLNTQV DHHHHHH

Attributs du produit: Recombinant Human Apolipoprotein A1/APOA1 produced by transfected human cells is a secreted protein with sequence (R19-Q267) of Human APOA1 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: APOA1 (Apolipoprotein A-I (APOA1))

Autre désignation: ApoA1 (APOA1 Produits)

Synonymes: Alp-1 Protein, Apoa-1 Protein, Brp-14 Protein, Ltw-1 Protein, Lvtw-1 Protein, Sep-1 Protein, Sep-2 Protein, Sep2 Protein, apoA-I Protein, apoa Protein, apoa1 Protein, cb49 Protein, wu:fb33f01 Protein, zgc:103718 Protein, MGC64335 Protein, MGC89745 Protein, Apo-AI Protein, ApoA-I Protein, APOA1 Protein, LOC100136573 Protein, apoa-i Protein, ApoAI Protein, apolipoprotein A1 Protein, apolipoprotein A-I Protein, apolipoprotein A-Ia Protein, apolipoprotein A-I S homeolog Protein, apolipoprotein A4 Protein, APOA1 Protein, Apoa1 Protein, apoa1a Protein, apoa1.S Protein, apoa1 Protein, LOC100136573 Protein, apoa-i Protein, apoa4 Protein

Sub Type: Fusionprotein

Sujet: Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
Synonyms: Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, APOA1

Poids moléculaire: 30 kDa

UniProt: P02647

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism