ASS1 Protein (AA 1-412) (His tag)
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- Antigène Voir toutes ASS1 Protéines
- ASS1 (Argininosuccinate Synthase 1 (ASS1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-412
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette ASS1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human Argininosuccinate Synthase/ASS1 (N-6His)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MSSKGSVVLA YSGGLDTSCI LVWLKEQGYD VIAYLANIGQ KEDFEEARKK ALKLGAKKVF IEDVSREFVE EFIWPAIQSS ALYEDRYLLG TSLARPCIAR KQVEIAQREG AKYVSHGATG KGNDQVRFEL SCYSLAPQIK VIAPWRMPEF YNRFKGRNDL MEYAKQHGIP IPVTPKNPWS MDENLMHISY EAGILENPKN QAPPGLYTKT QDPAKAPNTP DILEIEFKKG VPVKVTNVKD GTTHQTSLEL FMYLNEVAGK HGVGRIDIVE NRFIGMKSRG IYETPAGTIL YHAHLDIEAF TMDREVRKIK QGLGLKFAEL VYTGFWHSPE CEFVRHCIAK SQERVEGKVQ VSVLKGQVYI LGRESPLSLY NEELVSMNVQ GDYEPTDATG FININSLRLK EYHRLQSKVT AK
- Attributs du produit
- Recombinant Human Argininosuccinate Synthase/ASS1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys412) of Human ASS1 fused with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ASS1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 50 mM Imidazole, 1 mM DTT, 40 % Glycerol, pH 7.5.
- Agent conservateur
- Dithiothreitol (DTT)
- Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- -80 °C
- Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Date de péremption
- 6 months
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- Antigène
- ASS1 (Argininosuccinate Synthase 1 (ASS1))
- Autre désignation
- Argininosuccinate Synthase/ASS1 (ASS1 Produits)
- Synonymes
- ASS Protein, CTLN1 Protein, AA408052 Protein, Ass-1 Protein, fold Protein, ASSA Protein, Ass Protein, ass Protein, zgc:92051 Protein, wu:fb95a04 Protein, wu:fc01e08 Protein, argininosuccinate synthase 1 Protein, argininosuccinate synthetase 1 Protein, argininosuccinate synthase 1 S homeolog Protein, ASS1 Protein, Ass1 Protein, ass1.S Protein, ass1 Protein
- Sub Type
- Fusionprotein
- Sujet
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Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
Alternative Names: Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS - Poids moléculaire
- 42.8 kDa
- UniProt
- P00966
- Pathways
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin
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