Cathepsin L2 Protein (CTSL2) (AA 18-334) (His tag)

N° du produit ABIN1096248

Détail du produit

Antigène: Cathepsin L2 (CTSL2)

Type de proteíne: Recombinant

Attributs du protein: AA 18-334

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Cathepsin L2 protéine est marqué à la His tag.

Fonction: Recombinant Human Cathepsin L2/CTSL2 (C-6His)

Séquence: VPKFDQNLDT KWYQWKATHR RLYGANEEGW RRAVWEKNMK MIELHNGEYS QGKHGFTMAM NAFGDMTNEE FRQMMGCFRN QKFRKGKVFR EPLFLDLPKS VDWRKKGYVT PVKNQKQCGS CWAFSATGAL EGQMFRKTGK LVSLSEQNLV DCSRPQGNQG CNGGFMARAF QYVKENGGLD SEESYPYVAV DEICKYRPEN SVANDTGFTV VAPGKEKALM KAVATVGPIS VAMDAGHSSF QFYKSGIYFE PDCSSKNLDH GVLVVGYGFE GANSNNSKYW LVKNSWGPEW GSNGYVKIAK DKNNHCGIAT AASYPNVVDH HHHHH

Attributs du produit:

Recombinant Human Cathepsin L2/CTSL2 (C-6His)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Cathepsin L2 (CTSL2)

Autre désignation: Cathepsin L2 (CTSL2 Produits)

Synonymes: CATL2 Protein, CTSL2 Protein, CTSU Protein, CTSL Protein, CTSL1 Protein, ctsl2 Protein, LOC100232421 Protein, cathepsin V Protein, cathepsin V L homeolog Protein, cathepsin L Protein, CTSV Protein, ctsv.L Protein, ctsv Protein, CTSL Protein, Ctsv Protein

Sujet: Recombinant Human Cathepsin L2 produced by transfected human cells is a secreted protein with sequence (Val18-Val384) of Human CTSL2 fused with a polyhistidine tag at the C-terminus.
Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically converted to the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.

Poids moléculaire: 36.69 kDa

UniProt: O60911

Pathways: Toll-Like Receptors Cascades