CHI3L2 Protein (AA 27-390) (His tag)

N° du produit ABIN1096383

Détail du produit

Antigène: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Type de proteíne: Recombinant

Attributs du protein: AA 27-390

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CHI3L2 protéine est marqué à la His tag.

Fonction: Recombinant Human Chitinase 3-Like Protein 2/CHI3L2 (C-6His)

Séquence: YKLVCYFTNW SQDRQEPGKF TPENIDPFLC SHLIYSFASI ENNKVIIKDK SEVMLYQTIN SLKTKNPKLK ILLSIGGYLF GSKGFHPMVD SSTSRLEFIN SIILFLRNHN FDGLDVSWIY PDQKENTHFT VLIHELAEAF QKDFTKSTKE RLLLTVGVSA GRQMIDNSYQ VEKLAKDLDF INLLSFDFHG SWEKPLITGH NSPLSKGWQD RGPSSYYNVE YAVGYWIHKG MPSEKVVMGI PTYGHSFTLA SAETTVGAPA SGPGAAGPIT ESSGFLAYYE ICQFLKGAKI TRLQDQQVPY AVKGNQWVGY DDVKSMETKV QFLKNLNLGG AMIWSIDMDD FTGKSCNQGP YPLVQAVKRS LGSLVDHHHH HH

Attributs du produit: Recombinant Human Chitinase 3-Like Protein 2/CHI3L2 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Tyr27-Leu390) of Human CHI3L2 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Autre désignation: chitinase-3-like-2 (CHI3L2 Produits)

Synonymes: CHIL2 Protein, YKL-39 Protein, YKL39 Protein, chitinase 3 like 2 Protein, CHI3L2 Protein

Sub Type: Fusionprotein

Sujet: Chitinase 3-Like Protein 2 (CHI3L2) is a 39 kDa secreted glycoprotein which belongs to the glycosyl hydrolase 18 family and the most closely related to human cartilage glycoprotein 39, which promotes the growth of human synovial cells as well as skin and fetal lung fibroblasts. Highest expression of CHI3L2 is in chondrocytes, followed by synoviocytes, lung and heart. It is not detected in spleen, pancreas, and liver. CHI3L2 may also be expressed in developing brain and placenta. Increased levels of CHI3L2 have been demonstrated in synovial fluids of patients with rheumatoid or osteoarthritis as well as in some other pathologies and in malignant tumors, particularly in glioblastomas. CHI3L2 may bind glycan structure with high affinity, but not heparin. It has has no chitotriosidase activity, but is likely to bind some type of glycan.
Alternative Names: Chitinase-3-Like Protein 2, Chondrocyte Protein 39, YKL-39, CHI3L2

Poids moléculaire: 41.94 kDa

UniProt: Q15782