Elastase 4 Protein (AA 17-268) (His tag)

N° du produit ABIN1691229

Détail du produit

Antigène: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Type de proteíne: Recombinant

Attributs du protein: AA 17-268

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Elastase 4 protéine est marqué à la His tag.

Fonction: Recombinant Human Chymotrypsin-C/CTRC (C-6His)

Séquence: CGVPSFPPNL SARVVGGEDA RPHSWPWQIS LQYLKNDTWR HTCGGTLIAS NFVLTAAHCI SNTRTYRVAV GKNNLEVEDE EGSLFVGVDT IHVHKRWNAL LLRNDIALIK LAEHVELSDT IQVACLPEKD SLLPKDYPCY VTGWGRLWTN GPIADKLQQG LQPVVDHATC SRIDWWGFRV KKTMVCAGGD GVISACNGDS GGPLNCQLEN GSWEVFGIVS FGSRRGCNTR KKPVVYTRVS AYIDWINEKM QLVDHHHHHH

Attributs du produit: Recombinant Human Chymotrypsin-C/CTRC produced by transfected human cells is a secreted protein with sequence (Cys17-Leu268) of Human CTRC fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Autre désignation: chymotrypsin-c (CTRC Produits)

Synonymes: CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein

Sub Type: Fusionprotein

Sujet: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers to cleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Alternative Names: Chymotrypsin-C, Caldecrin, CTRC, CLCR

Poids moléculaire: 29 kDa

UniProt: Q99895