HEPACAM Protein (AA 34-240) (His tag)

N° du produit ABIN1096816

Détail du produit

Antigène: HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))

Type de proteíne: Recombinant

Attributs du protein: AA 34-240

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette HEPACAM protéine est marqué à la His tag.

Fonction: Recombinant Human Hepatocyte Cell Adhesion Molecule/HepaCAM (C-6His)

Séquence: VNITSPVRLI HGTVGKSALL SVQYSSTSSD RPVVKWQLKR DKPVTVVQSI GTEVIGTLRP DYRDRIRLFE NGSLLLSDLQ LADEGTYEVE ISITDDTFTG EKTINLTVDV PISRPQVLVA STTVLELSEA FTLNCSHENG TKPSYTWLKD GKPLLNDSRM LLSPDQKVLT ITRVLMEDDD LYSCMVENPI SQGRSLPVKI TVYRRSSVDH HHHHH

Attributs du produit: Recombinant Human Hepatocyte Cell Adhesion Molecule/HEPACAM produced by transfected human cellss is a secreted protein with sequence (Val34-Ser240) of Human HEPACAM fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))

Autre désignation: hepacam (HEPACAM Produits)

Synonymes: GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein

Sub Type: Fusionprotein

Sujet: Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
Alternative Names: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM

Poids moléculaire: 24.09 kDa

UniProt: Q14CZ8