PMVK Protein (AA 1-192) (His tag)

N° du produit ABIN1097355

Détail du produit

Antigène: PMVK (Phosphomevalonate Kinase (PMVK))

Type de proteíne: Recombinant

Attributs du protein: AA 1-192

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PMVK protéine est marqué à la His tag.

Fonction: Recombinant Human Phosphomevalonate Kinase/PMVK (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MAPLGGAPRL VLLFSGKRKS GKDFVTEALQ SRLGADVCAV LRLSGPLKEQ YAQEHGLNFQ RLLDTSTYKE AFRKDMIRWG EEKRQADPGF FCRKIVEGIS QPIWLVSDTR RVSDIQWFRE AYGAVTQTVR VVALEQSRQQ RGWVFTPGVD DAESECGLDN FGDFDWVIEN HGVEQRLEEQ LENLIEFIRS RL

Attributs du produit: Recombinant Human Phosphomevalonate Kinase/PMVK is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Leu192) of Human PMVK fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PMVK (Phosphomevalonate Kinase (PMVK))

Autre désignation: Phosphomevalonate Kinase/PMVK (PMVK Produits)

Synonymes: MPK_Bm Protein, F5M6.9 Protein, F5M6_9 Protein, zgc:162701 Protein, HUMPMKI Protein, PMK Protein, PMKA Protein, PMKASE Protein, 1110011E12Rik Protein, 2900002L22Rik Protein, AV001327 Protein, phosphomevalonate kinase Protein, GHMP kinase family protein Protein, PMVK Protein, Mpk Protein, AT1G31910 Protein, CpipJ_CPIJ015413 Protein, Bm1_05275 Protein, pmvk Protein, LOAG_11811 Protein, Tsp_06629 Protein, LOC100282968 Protein, Pmvk Protein

Sub Type: Fusionprotein

Sujet: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney, it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
Alternative Names: Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI

Poids moléculaire: 24.2 kDa

UniProt: Q15126