UBE2H Protein (AA 1-183) (GST tag)

N° du produit ABIN1097724

Détail du produit

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Type de proteíne: Recombinant

Attributs du protein: AA 1-183

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2H protéine est marqué à la GST tag.

Fonction: Recombinant Human Ubiquitin-Conjugating Enzyme E2 H/UBE2H (N-GST)

Séquence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMSS PSPGKRRMDT DVVKLIESKH EVTILGGLNE FVVKFYGPQG TPYEGGVWKV RVDLPDKYPF KSPSIGFMNK IFHPNIDEAS GTVCLDVINQ TWTALYDLTN IFESFLPQLL AYPNPIDPLN GDAAAMYLHR PEEYKQKIKE YIQKYATEEA LKEQEEGTGD SSSESSMSDF SEDEAQDMEL

Attributs du produit: Recombinant Human Ubiquitin-Conjugating Enzyme E2 H/UBE2H is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu183) of Human UBE2H fused with a GST tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Autre désignation: Ubiquitin-Conjugating Enzyme E2 H/UBE2H (UBE2H Produits)

Synonymes: fc07a05 Protein, fi24c01 Protein, wu:fc07a05 Protein, wu:fi24c01 Protein, si:bz3c13.2 Protein, e2-20k Protein, ubc8 Protein, ubch Protein, ubch2 Protein, E2-20K Protein, GID3 Protein, UBC8 Protein, UBCH Protein, UBCH2 Protein, 1500009C23Rik Protein, AI181839 Protein, AI326965 Protein, AI462483 Protein, AW227540 Protein, Gid3 Protein, N28148 Protein, Ubc8 Protein, ubiquitin conjugating enzyme E2 H Protein, ubiquitin-conjugating enzyme E2 H Protein, Ubiquitin-conjugating enzyme E2 H Protein, ubiquitin conjugating enzyme E2H S homeolog Protein, ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2-21 KD Protein, ubiquitin-conjugating enzyme E2H Protein, UBE2H Protein, CpipJ_CPIJ015105 Protein, Bm1_31760 Protein, PTRG_01621 Protein, LOAG_08716 Protein, ube2h.S Protein, ube2h Protein, uce-E2 Protein, uceE2 Protein, Ube2h Protein

Sub Type: Fusionprotein

Sujet: Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
Alternative Names: Ubiquitin-Conjugating Enzyme E2 H, UbcH2, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Protein Ligase H, UBE2H

Poids moléculaire: 47 kDa

UniProt: P62256