UBE2H Protein (GST tag)

N° du produit ABIN7319267

Détail du produit

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2H protéine est marqué à la GST tag.

Fonction: Recombinant Human Ube2H Protein (GST Tag)

Séquence: Met 1-Leu183

Attributs du produit: Recombinant Human Ubiquitin-Conjugating Enzyme E2 H is produced by our E.coli expression system and the target gene encoding Met1-Leu183 is expressed with a GST tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Autre désignation: Ube2H (UBE2H Produits)

Synonymes: fc07a05 Protein, fi24c01 Protein, wu:fc07a05 Protein, wu:fi24c01 Protein, si:bz3c13.2 Protein, e2-20k Protein, ubc8 Protein, ubch Protein, ubch2 Protein, E2-20K Protein, GID3 Protein, UBC8 Protein, UBCH Protein, UBCH2 Protein, 1500009C23Rik Protein, AI181839 Protein, AI326965 Protein, AI462483 Protein, AW227540 Protein, Gid3 Protein, N28148 Protein, Ubc8 Protein, ubiquitin conjugating enzyme E2 H Protein, ubiquitin-conjugating enzyme E2 H Protein, Ubiquitin-conjugating enzyme E2 H Protein, ubiquitin conjugating enzyme E2H S homeolog Protein, ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2-21 KD Protein, ubiquitin-conjugating enzyme E2H Protein, UBE2H Protein, CpipJ_CPIJ015105 Protein, Bm1_31760 Protein, PTRG_01621 Protein, LOAG_08716 Protein, ube2h.S Protein, ube2h Protein, uce-E2 Protein, uceE2 Protein, Ube2h Protein

Sujet:

Background: Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

Synonym: Ubiquitin-Conjugating Enzyme E2 H, UbcH2, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Protein Ligase H, UBE2H,E2-20K,GID3,UBC8,UBCH,UBCH2

Poids moléculaire: 47.0 kDa

UniProt: P62256