ADH5 Protein (His tag)

N° du produit ABIN1098240

Détail du produit

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ADH5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Alcohol dehydrogenase class-3, ADHX, FDH

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH7.5) containing 20% glycerol 0.1 M Nacl, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Autre désignation: ADH5 (ADH5 Produits)

Synonymes: ADH2 Protein, ADH-3 Protein, ADHX Protein, FALDH Protein, FDH Protein, GSH-FDH Protein, GSNOR Protein, ADH1C Protein, ADH3 Protein, wu:fb60b11 Protein, Adh-5 Protein, Adh3 Protein, adh-3 Protein, adh3 Protein, adh5 Protein, adhx Protein, fdh Protein, gsnor Protein, ADH4 Protein, ADH5 Protein, alcohol dehydrogenase 1B (class I), beta polypeptide Protein, alcohol dehydrogenase 5 (class III), chi polypeptide Protein, alcohol dehydrogenase 5 Protein, alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog Protein, alcohol dehydrogenase class-3 Protein, ADH1B Protein, ADH5 Protein, adh5 Protein, Adh5 Protein, adh5.L Protein, LOC101112223 Protein

Sujet: ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. Recombinant human ADH5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 42.3 kDa (398aa), confirmed by MALDI-TOF

NCBI Accession: NP_000662