HAAO Protein (His tag)
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- Antigène Voir toutes HAAO Protéines
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette HAAO protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HAAO Protéine
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3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (His tag)
HAAO Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (GST tag)HAAO Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) protein (GST tag)HAAO Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) protein (His tag)HAAO Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) protein (Myc-DYKDDDDK Tag)HAAO Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Commentaires
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Synonyms: 3-hydroxyanthranilate 3, 4-dioxygenase, 3-HAO, HAO
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by BCA assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- Autre désignation
- HAAO (HAAO Produits)
- Synonymes
- Afu2g17450 Protein, 0610007K21Rik Protein, 0610012J07Rik Protein, 3-HAO Protein, 3-HAOxase Protein, 3HAO Protein, zgc:103585 Protein, HAO Protein, 3-hydroxyanthranilate 3,4-dioxygenase Protein, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog Protein, SPO1774 Protein, CNB05620 Protein, AFUA_2G17450 Protein, Bcep18194_C7641 Protein, Kfla_5491 Protein, Micau_4935 Protein, RBRH_03005 Protein, Krodi_1278 Protein, haao Protein, HAAO Protein, Haao Protein, haao.L Protein
- Sujet
- HAAO is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. This protein catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Recombinant human HAAO protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 35kDa (310aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_036337
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