NMRK1 Protein (His tag)

N° du produit ABIN1098295

Détail du produit

Antigène: NMRK1 (Nicotinamide Riboside Kinase 1 (NMRK1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NMRK1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: nicotinamide riboside kinase 1 isoform 1, bA235O14.2, NRK1, RP11-235O14.2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 2 mM DTT, 200 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NMRK1 (Nicotinamide Riboside Kinase 1 (NMRK1))

Autre désignation: NRK1 (NMRK1 Produits)

Synonymes: C9orf95 Protein, NRK1 Protein, bA235O14.2 Protein, AA408380 Protein, D630020N23Rik Protein, Nrk1 Protein, zgc:113113 Protein, nicotinamide riboside kinase 1 Protein, NMRK1 Protein, Nmrk1 Protein, nmrk1 Protein

Sujet: NRK1 belongs to the uridine kinase family. NAD+ is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in various reactions, including those that retard aging in experimental systems. Nicotinic acid and nicotinamide were defined as the vitamin precursors of NAD+. This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine. Recombinant human NRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25.6kDa (222aa), confirmed by MALDI-TOF

NCBI Accession: NP_060351