SNF8 Protein (His tag)

N° du produit ABIN1098312

Détail du produit

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SNF8 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Vacuolar-sorting protein SNF8, Dot3, EAP30, VPS22

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 50% glycerol, 2 mM DTT, 200 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Autre désignation: SNF8 (SNF8 Produits)

Synonymes: d11moh34 Protein, vps22 Protein, Dot3 Protein, EAP30 Protein, VPS22 Protein, D11moh34 Protein, RGD1310144 Protein, D11Moh34 Protein, D11MOH34 Protein, zgc:101578 Protein, SNF8, ESCRT-II complex subunit Protein, eap30 subunit of ell complex, putative Protein, EAP30 subunit of ELL complex Protein, SNF8, ESCRT-II complex subunit S homeolog Protein, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) Protein, snf8 Protein, TA17290 Protein, TVAG_107410 Protein, Bm1_05145 Protein, SNF8 Protein, Snf8 Protein, snf8.S Protein

Sujet: SNF 8, also known as EAP30 (ELL-associated protein of 30 kDa), is localizes to both the nucleus and the cytoplasm and is a member of the SNF8 family of vacuolar sorting proteins. This protein is subunit of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Recombinant human SNF8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 31.4kDa (282aa) confirmed by MALDI-TOF

NCBI Accession: NP_009172