HBXIP Protein (His tag)

N° du produit ABIN1098350

Détail du produit

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HBXIP protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Hepatitis B virus x interacting protein, XIP

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM EDTA

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Autre désignation: HBXIP (HBXIP Produits)

Synonymes: HBXIP Protein, xip Protein, XIP Protein, 1110003H18Rik Protein, Hbxip Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Protein, Hepatitis B virus X-interacting protein Protein, LAMTOR5 Protein, xip Protein, Lamtor5 Protein

Classe de substances: Viral Protein

Sujet: Hepatitis B virus x interacting protein, also known as HBXIP, was originally identified by its ability to form a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates the activity of HBX and alters the replicative life cycle of the virus. In addition, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly through an interaction with Dynein light chain. Recombinant human HBXIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 20.7 kDa (197aa) confirmed by MALDI-TOF

NCBI Accession: NP_006393

Pathways: Signalisation PI3K-Akt, Regulation of Cell Size