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Asialoglycoprotein Receptor 2 Protein (ASGR2) (His tag)

ASGR2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN1098437
  • Antigène Voir toutes Asialoglycoprotein Receptor 2 (ASGR2) Protéines
    Asialoglycoprotein Receptor 2 (ASGR2)
    Type de proteíne
    Recombinant
    Origine
    • 7
    • 3
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Asialoglycoprotein Receptor 2 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ASGR2 Protéine
  • Commentaires

    Synonyms: Asialoglycoprotein receptor 2, ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    Asialoglycoprotein Receptor 2 (ASGR2)
    Autre désignation
    ASGR2 (ASGR2 Produits)
    Synonymes
    ASGR2 Protein, asgr2 Protein, MGC137129 Protein, ASGP-R2 Protein, ASGPR2 Protein, CLEC4H2 Protein, HBXBP Protein, HL-2 Protein, Asgr Protein, Asgr-2 Protein, asialoglycoprotein receptor 2 Protein, C-type lectin domain family 10 member A Protein, ASGR2 Protein, clec10a Protein, Asgr2 Protein, LOC100347178 Protein
    Sujet
    ASGR2 is a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. It may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2 is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human ASGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    28.9 kDa (255aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001172
    Pathways
    Thyroid Hormone Synthesis
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