GULP1 Protein (His tag)

N° du produit ABIN1098569

Détail du produit

Antigène: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GULP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: PTB domain-containing engulfment adapter protein 1, CED-6, CED6, GULP

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 50% glycerol, 2 mM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Autre désignation: GULP1 (GULP1 Produits)

Synonymes: GULP1 Protein, CED-6 Protein, CED6 Protein, GULP Protein, 3110030A04Rik Protein, 5730529O06Rik Protein, Ced6 Protein, Gulp-2 Protein, gulp1 Protein, si:by35d8.1 Protein, si:ch211-198b21.4 Protein, si:xx-35d8.1 Protein, wu:fj61e02 Protein, GULP, engulfment adaptor PTB domain containing 1 Protein, CED-6 protein Protein, ced-6 protein Protein, GULP, engulfment adaptor PTB domain containing 1a Protein, GULP1 Protein, gulp1 Protein, Bm1_18525 Protein, ced-6 Protein, Gulp1 Protein, gulp1a Protein

Sujet: PTB domain-containing engulfment adapter protein 1, also known as GULP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GULP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GULP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 36.9kDa (327aa) confirmed by MALDI-TOF

NCBI Accession: NP_057399